E-GEOD-58725 - Expression data from embryonic stem cells (ESCs) and ESC-like cells
Released on 23 June 2014, last updated on 28 June 2014
The transplantation of ESCs into living recipients causes teratoma formation which accompanies with several biological reactions in both the transplanted cells and recipient. Co-injection of ESCs with somatic cells that influence donor-recipient homogeneity can affect transcriptional profile of transplanted ESCs. We investigated global gene expression of parental ESCs and ESC-like cells derived from teratomas which were formed by different injection conditions to find transcriptional differences according to donor-recipient homogeneity and somatic cell co-injection. Parental ESCs or teratoma-derived ESC-like cells from different treatments were retrieved for RNA extraction and hybridization on Affymetrix microarrays.
transcription profiling by array
Jeong Mook Lim <email@example.com>, Boyun Kim, Jae-Wook Jeong, Jeong M Lim, Seung P Gong