Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-58673 - Transcriptional profiling of PRDM2 Knock down vs.controlGFPsh differentiated C2C12 Myoblasts (D28hrs)
Released on 30 June 2015, last updated on 19 August 2015
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of 28hr differentiated myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using affymetrix mouse chips. Control and knock down cells were grown in differentiating conditions for 28hrs and total RNA was used to perform microarray analysis
transcription profiling by array
Sirisha Cheedipudi <email@example.com>, Amena Saleh, Deepika Puri, Hardik Gala, Henrik D Schroeder, Jeeva Sellathurai, Jyotsna Dhawan, Malini S Pillai, Mohammed Rumman, Prethish Srinivas, Rakesh Mishra, Reety Arora
A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene. Cheedipudi S, Puri D, Saleh A, Gala HP, Rumman M, Pillai MS, Sreenivas P, Arora R, Sellathurai J, Schroeder HD, Mishra RK, Dhawan J.