E-GEOD-58360 - Gene expression changes after loss of C/EBPα in transformed HSCs [CEBPA RNA-seq]
Released on 11 June 2014, last updated on 13 August 2014
RNAseq characterization of gene expression changes 72 hours after genomic excision of Cebpa in murine hematopoietic progenitors from Cebpaf/f;CreER mice transformed by Hoxa9/Meis1. In the presence of tamoxifen (4OHT), Cre-ER localizes to the nucleus of cells allowing for excision of Cebpa and loss of C/EBPα protein levels. Loss of C/EBPα leads to a decrease in cellular proliferation. Examination of gene expression by RNAseq in two conditions in biological replicates.
RNA-seq of coding RNA
Jay L. Hess <firstname.lastname@example.org>, Jay L Hess