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E-GEOD-57643 - LncRNAs expression profiling in adipose tissues and during brown adipocyte differentiation

Released on 28 February 2015, last updated on 7 March 2015
Mus musculus
Samples (10)
Array (1)
Protocols (6)
Brown and beige fats generate heat via uncoupled respiration to defend against cold, mechanistically, through the action of a network of transcription factors and cofactors. Here we globally profiled long noncoding RNAs (lncRNAs) gene expression during thermogenic adipocyte formation and identified Brown fat lncRNA 1 (Blnc1) as a novel nuclear lncRNA that promotes brown and beige adipocyte differentiation and function by forming a feedforward regulatory loop with EBF2 to drive adipogenesis toward thermogenic phenotype. LncRNAs expression were measured in BAT and WAT from mice injected saline/CL and during brown adipocyte differentiation with two replicates using Arraystar Mouse LncRNA microarray V2.0
Experiment type
transcription profiling by array 
xuyun zhao <>, Guo-Xiao Wang, Jiandie D Lin, Qi Yu, Siming Li, Xu-Yun Zhao
Investigation descriptionE-GEOD-57643.idf.txt
Sample and data relationshipE-GEOD-57643.sdrf.txt
Raw data (1)
Processed data (1)
Array designA-GEOD-15691.adf.txt