E-GEOD-57285 - DNA methylation profiling of whole blood DNA samples from BRCA1 wild-types without breast cancer and BRCA1 mutants with and without breast cancer (Prague Set 1)

Status
Released on 6 May 2014, last updated on 3 June 2014
Organism
Homo sapiens
Samples (84)
Array (1)
Protocols (5)
Description
The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in whole blood DNA samples from 84 women (42 BRCA1 wild-type and healthy, 7 BRCA1 mutants and healthy, 35 BRCA1 mutants with breast cancer) whole blood DNA from women, with and without breast cancer, and with or without BRCA1 mutation Bisulphite converted DNA from the whole blood samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2 The BRCA1 mutation status represent 0=healthy-brca1wt, 1=healthy-brca1mt, 2=breastcancer-brca1mt.
Experiment type
methylation profiling by array 
Contacts
Andrew E Teschendorff <a.teschendorff@ucl.ac.uk>, Andrew Teschendorff, Martin Widschwendter
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-57285.idf.txt
Sample and data relationshipE-GEOD-57285.sdrf.txt
Raw data (1)E-GEOD-57285.raw.1.zip
Processed data (1)E-GEOD-57285.processed.1.zip
Array designA-GEOD-8490.adf.txt
Links