Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-56945 - Regulatory consequences of TARBP2 knock-down in293T cell-line
Released on 24 July 2014, last updated on 5 August 2014
siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts. Two independent siRNAs were used to knock down TARBP2 in metastatic 293T cells. The cells were then subjected to transcripome profiling in comparison to mock-transfected cells.
transcription profiling by array
Hani Goodarzi <email@example.com>, C G Buss, H Goodarzi, L Fish, S F Tavazoie, S Tavazoie, S Zhang
Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF. , PMID:25043050