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E-GEOD-5596 - Suz12 ChIP-chip using Avi-6k-hu
Submitted on 23 August 2006, released on 25 June 2010, last updated on 4 May 2014
The polycomb group (PcG) protein, EZH2, possesses oncogenic properties for which the underlying mechanism is unclear. In this set of experiments, we sought to identify a robust set of Suz12-occupied gene promoters in prostate cancer cell lines. Genome-wide location analysis (ChIP-chip) of SUZ12 was performed in both the PC3 and LNCaP prostate cancer cell lines using an IgG ChIP-chip as a control. There are total 3 hybridizations, including IgG ChIP-chip of PC3 cells, Suz12 ChIP-chip of PC3 and LNCaP cells.
unknown experiment type
Jindan Yu <firstname.lastname@example.org>, Arul M Chinnaiyan
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Yu J, Cao Q, Mehra R, Laxman B, Yu J, Tomlins SA, Creighton CJ, Dhanasekaran SM, Shen R, Chen G, Morris DS, Marquez VE, Shah RB, Ghosh D, Varambally S, Chinnaiyan AM.