Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-55389 - Expression data from whole retina of 8-week old db/db diabetic mice and lean littermates

Status
Released on 27 February 2014, last updated on 14 March 2014
Organism
Mus musculus
Samples (8)
Array (1)
Protocols (7)
Description
Diabetic retinopathy is one of the leading causes of blindness in diabetic patients. Emerging evidence suggests that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy, but the underlying causes of neuronal loss are unknown. To unravel potential mechanisms underlying early retinal neurodegeneration in diabetic retinopathy, a gene expression profiling study was undertaken to compare the gene expression in retinas of 8-week db/db diabetic mice with that of lean non-diabetic littermates. Retinas were obtained from 8-week db/db diabetic mice and age-matched lean non-diabetic controls. Total RNA was extracted and processed for being hybridized onto affymetrix DNA microarrays.
Experiment type
transcription profiling by array 
Contacts
Cristina Hernández, Josep A Villena, Lidia Corraliza, Patrica Bogdanov, Rafael Simó
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-55389.idf.txt
Sample and data relationshipE-GEOD-55389.sdrf.txt
Raw data (1)E-GEOD-55389.raw.1.zip
Processed data (1)E-GEOD-55389.processed.1.zip
Array designA-AFFY-130.adf.txt
Links