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E-GEOD-55376 - small RNAseq analysis of the global retinal transcriptome of rod photoreceptor-specific Dicer1 conditional knockout mice and control littermates

Status
Released on 14 August 2014, last updated on 10 December 2014
Organism
Mus musculus
Samples (6)
Protocols (2)
Description
We report RNAseq analysis of the transcriptome of retinas from mature rod-specific Dicer1 cKO mice and control littermates lacking Cre expression in order to better understand changes in gene regulation that could lead to retinal degeneration in cKO mice. Examine retinal transcriptome of 3 biological replicates for each genotype from 4-week-old animals with tissue collected between 8:00 - 10:00AM
Experiment type
RNA-seq of non coding RNA 
Contacts
Xiaodong Bai <geo@ncbi.nlm.nih.gov>, Krzysztof Palczewski, Thomas Sundermeier
Citation
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice. Sundermeier TR, Zhang N, Vinberg F, Mustafi D, Kohno H, Golczak M, Bai X, Maeda A, Kefalov VJ, Palczewski K. , PMID:24812086
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-55376.idf.txt
Sample and data relationshipE-GEOD-55376.sdrf.txt
Additional data (1)E-GEOD-55376.additional.1.zip
Links