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E-GEOD-54044 - Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function (Expression data from islets of control and Insm1 conditional deleted adult pancreatic islets)

Status
Released on 31 March 2015, last updated on 4 April 2015
Organism
Mus musculus
Samples (16)
Array (1)
Protocols (5)
Description
The zinc finger factor Insm1 is known to regulate differentiation of pancreatic β cells during development, Here we show that Insm1 is essential for the maintenance of functionally mature pancreatic β cells in mice. We used microarrays to analyse the global gene expression after deletion of insm1 in adult pancreatic β cells and identified functional important genes and immature islets releated genes deregulated in the mutatant islets. We used 8 mutant and 8 litter matched control mice for the islets preparation.
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-54044.idf.txt
Sample and data relationshipE-GEOD-54044.sdrf.txt
Raw data (1)E-GEOD-54044.raw.1.zip
Processed data (1)E-GEOD-54044.processed.1.zip
Array designA-AFFY-45.adf.txt
Links