Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-53042 - Copy number variation comparison between control and CC214-2 resistant GBM39 xenografts
Released on 6 December 2013, last updated on 4 May 2014
Here we present genome-wide copy number variation data on two vehicle treated and two CC214-2 (an mTOR kinase inhibitor) resistant GlioBlastoma Multiforme 39 (GBM39) xenografts, showing the absence of significant differences between the two groups, demonstrating that resistance to CC214-2 is due to adaptation rather than gene mutations. The genomic DNA extracted from the 4 xenografts samples was analysed with genome-wide Affymetrix SNP6.0 array
comparative genomic hybridization by array
Paul Mischel <firstname.lastname@example.org>, James R Heath, Paul S Mischel