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E-GEOD-52514 - Differential gene expression in nephron progenitors lacking miR-17~92

Status
Released on 7 March 2014, last updated on 15 April 2014
Organism
Mus musculus
Samples (6)
Protocols (2)
Description
Purpose: The goal of this study is to compare the differential expression of transcripts in control kidneys compared to kidneys lacking the miR-17~92 cluster in nephron progenitors and their derivatives by RNA-seq to identify potential miRNA targets in the mutant kidneys. mRNA profiles of control and mutant (=Six2-TGC; miR-17~92 flx/flx) embryonic day 16 kidneys were generated by deep sequencing, in triplicate, using Illumina HiSeq2000
Experiment type
RNA-seq of coding RNA 
Contacts
April K Marrone, Dennis Kostka, Jacqueline Ho
Citation
MicroRNA-17~92 Is Required for Nephrogenesis and Renal Function. Marrone AK, Stolz DB, Bastacky SI, Kostka D, Bodnar AJ, Ho J. , PMID:24511118
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-52514.idf.txt
Sample and data relationshipE-GEOD-52514.sdrf.txt
Additional data (1)E-GEOD-52514.additional.1.zip
Links