E-GEOD-51866 - Gene expression data for liver, adipose, and skeletal muscle tissues of MKR and Healthy mice

Status
Released on 30 October 2013, last updated on 3 June 2014
Organism
Mus musculus
Samples (18)
Array (1)
Protocols (7)
Description
MKR mice is a Type 2 Diabetic mice, which was created by expressing mutation in IGF1 receptor in the skeletal muscle, and is widely used in diabetes research. Gene expression differences between MKR mice and Healthy (Wild type) mice are poorly understood. We used microarrays to detail the differences between gene expression in liver, fat, and skeletal muscle of MKR and Healthy mice. Male 10-weeks old FVB/N – MKR and wild type mice were used for the microarray studies. 3 biological replicates for each tissue type and for both MKR and WT mice were used in the studies.
Experiment type
transcription profiling by array 
Contacts
Amit Kumar <amit.kumar3@nih.gov>, Chithra Keembiyehetty, Derek LeRoith, Emily J Gallagher, Joseph Shiloach, Michael J Betenbaugh
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-51866.idf.txt
Sample and data relationshipE-GEOD-51866.sdrf.txt
Raw data (1)E-GEOD-51866.raw.1.zip
Processed data (1)E-GEOD-51866.processed.1.zip
Array designA-GEOD-10740.adf.txt
Links