E-GEOD-51481 - Gene expression profiling of WWOX-overexpressing glioblastoma T98G cells

Released on 22 October 2013, last updated on 3 June 2014
Homo sapiens
Samples (8)
Array (1)
Protocols (7)
The WWOX gene is known for its tumor suppressor character and seems to be one of the main cellular regulators of cell cycle and apoptosis. The aim of the study was to identify cellular pathways and biological processes influenced by WWOX in glioblastoma cells. Our experiment showed that in this type of cancer WWOX, beside cell cycle and apoptosis control, may be involved in metabolism, cytoskeleton structure and differentiation. T98G glioblastoma cells were stably transfected with WWOX cDNA. T98G cells transfected with an empty vector served as a control. Total mRNA was isolated to look for gene-expression differences induced by the WWOX overexpression.
Experiment type
transcription profiling by array 
Karolina Pospiech <karolina.pospiech@umed.lodz.pl>, Andrzej K Bednarek, Katarzyna Kośla, Magdalena Nowakowska
Investigation descriptionE-GEOD-51481.idf.txt
Sample and data relationshipE-GEOD-51481.sdrf.txt
Raw data (1)E-GEOD-51481.raw.1.zip
Processed data (1)E-GEOD-51481.processed.1.zip
Array designA-GEOD-13693.adf.txt