Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-51013 - Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways
Status | Released on 18 February 2016, last updated on 27 February 2016 | ||||||||||
Organism | Danio rerio | ||||||||||
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Description | The mammalian heart has poor regenerative capacity following injury. In contrast, certain lower vertebrates such as zebrafish retain a robust capacity for regeneration into adult life. Here we use an integrated approach to identify evolutionary conserved regenerative miRNA-dependant regulatory circuits in the heart. We identified novel miRNA-dependant networks involved in critical biological pathways, which are differentially utilized between the infarcted mouse heart and the regenerating zebrafish heart. 2 conditions, 4 biological replicates per condition | ||||||||||
Experiment type | transcription profiling by array | ||||||||||
Contacts | Mark Ibberson <geo@ncbi.nlm.nih.gov>, Alexandre Sarre, Corinne Berthonneche, Daniel Schorderet, Dario Diviani, Gaëlle Boisset, Ioannis Xenarios, Keith Harshman, Mohammed Nemir, Samir Ounzain, Stefania Crippa, Thierry Pedrazzini | ||||||||||
Citation | Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways. Crippa S, Nemir M, Ounzain S, Ibberson M, Berthonneche C, Sarre A, Boisset G, Maison D, Harshman K, Xenarios I, Diviani D, Schorderet D, Pedrazzini T. , PMID:26857418 | ||||||||||
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