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E-GEOD-50002 - Effect of Twist-box mutation on gene expression induced by Twist1 overexpression

Status
Released on 20 August 2013, last updated on 2 September 2013
Organism
Mus musculus
Samples (15)
Array (1)
Protocols (6)
Description
Twist1 is a transcription factor that induces EMT and drives metastasis in prostate cancer. We examined global gene expression in Myc-CaP mouse prostate cancer cells following overexpression of Twist1 and the Twist1 mutants F191G, AQA, and DQD. 15 total samples were analysed, with 3 replicates of 5 groups: Twist1-WT, Twist1-AQA, Twist1-DQD, Twist1-F191G, and vector control. We performed the comparisons: WT > VEC, F191G > VEC. Samples were normalized by Twist1 expression in addition to normal
Experiment type
transcription profiling by array 
Contacts
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-50002.idf.txt
Sample and data relationshipE-GEOD-50002.sdrf.txt
Raw data (1)E-GEOD-50002.raw.1.zip
Processed data (1)E-GEOD-50002.processed.1.zip
Array designA-AFFY-130.adf.txt
Links