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E-GEOD-49248 - KrasG12D partially compensates for the loss of beta-catenin in MLL-AF9 AML

Status
Released on 2 July 2014, last updated on 16 July 2014
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (7)
Description
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-catenin for KrasG12DMLL-AF9 leukemia. Lin-Kit+ bone marrow cells obtained from mice transplanted with primary MLL-AF9 leukemia cells and KRasG12DMLL-AF9 leukemia cells were assessed for gene expression in the presence or absence of beta-catenin
Experiment type
transcription profiling by array 
Contacts
Amit Sinha <ausinha@gmail.com>, Cherry E Ng, Demetrios Kalaitzidis, Scott Armstrong
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-49248.idf.txt
Sample and data relationshipE-GEOD-49248.sdrf.txt
Raw data (1)E-GEOD-49248.raw.1.zip
Processed data (1)E-GEOD-49248.processed.1.zip
Array designA-AFFY-45.adf.txt
Links