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E-GEOD-49237 - Analysis of TBR1 downnstream target genes in embryonic forebrains

Status
Released on 31 December 2013, last updated on 20 July 2015
Organism
Mus musculus
Samples (8)
Array (1)
Protocols (7)
Description
TBR1 is a forebrain specific T-box transcription factor. Tbr1-/- mice have been characterized by defective axonal projections from cerebral cortex and abnormal neuronal migration of cerebral cortex and amygdala. To investigate how TBR1 regulates neural development, the gene expression profile of Tbr1-/- brains was compared with WT littermates. Total RNAs purified from forebrains at embryonic day 16.5 were hybridized on Affymetrix microarrays
Experiment type
transcription profiling by array 
Contacts
Citation
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-49237.idf.txt
Sample and data relationshipE-GEOD-49237.sdrf.txt
Raw data (1)E-GEOD-49237.raw.1.zip
Processed data (1)E-GEOD-49237.processed.1.zip
Array designA-AFFY-45.adf.txt
Links