Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-48392 - Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays
Released on 30 November 2013, last updated on 3 June 2014
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays, or 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Mammary tissue was collected 1 weeks, 4 weeks, and 12 weeks post-irradiation. Four radiation treatment groups: sham, 100 cGy sparsely ionizing gamma-rays, 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Three time points post-irradiation (1, 4, and 12 weeks). Three or four replicates per time point.
transcription profiling by array
Jonathan Tang <firstname.lastname@example.org>, David Nguyen, Haydeliz Martinez-Ruis, Ignacio Fernandez-Garcia, Irineu Bochaca, Jian-Hua Mao, Mary H Barcellos-Hoff, Sangeetha Vijayakumar, Sylvain V Costes
Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruiz H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes SV, Barcellos-Hoff MH. , PMID:24038768