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E-GEOD-48392 - Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays

Status
Released on 30 November 2013, last updated on 3 June 2014
Organism
Mus musculus
Samples (37)
Array (1)
Protocols (7)
Description
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays, or 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Mammary tissue was collected 1 weeks, 4 weeks, and 12 weeks post-irradiation. Four radiation treatment groups: sham, 100 cGy sparsely ionizing gamma-rays, 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Three time points post-irradiation (1, 4, and 12 weeks). Three or four replicates per time point.
Experiment type
transcription profiling by array 
Contacts
Jonathan Tang <jonathantang@lbl.gov>, David Nguyen, Haydeliz Martinez-Ruis, Ignacio Fernandez-Garcia, Irineu Bochaca, Jian-Hua Mao, Mary H Barcellos-Hoff, Sangeetha Vijayakumar, Sylvain V Costes
Citation
Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruiz H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes SV, Barcellos-Hoff MH. , PMID:24038768
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-48392.idf.txt
Sample and data relationshipE-GEOD-48392.sdrf.txt
Raw data (1)E-GEOD-48392.raw.1.zip
Processed data (1)E-GEOD-48392.processed.1.zip
Array designA-GEOD-11533.adf.txt
Links