E-GEOD-47786 - Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line
Released on 2 October 2013, last updated on 3 June 2014
Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Here, we used gene expression microarray to analyze gene expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DMSO as control. Comparing gene expression profiles of 40 µM berberine-treated HepG2 human hepatoma cell line to those of control cells sampled after 4 hours treatment. A 50 mM stock solution of Berberine chloride was prepared in DMSO. Cells were treated with 40 µM berberine chloride or 0.08% DMSO as control.
transcription profiling by array
Ting-fang Lo <email@example.com>, Shui-Tein Chen, Ting-Fang Lo