E-GEOD-47641 - Expression analysis of mock- or RAD21-transduced Kasumi1 cells
Released on 16 July 2013, last updated on 3 June 2014
We recently identified recurrent mutations of cohesin complex in myeloid neoplasms through whole-exome sequencing analysis. RAD21 is one of the main components of the cohesin complex. In this study, to investigate the biological impact of wild-type RAD21 on Kasumi1 cells harboring RAD21 mutation, Kasumi1 cells were retrovirally transduced with either mock or wild-type RAD21, and expression array was performed. Expression analysis was performed for mock- or wild-type RAD21-transduced Kasumi-1 cells in triplicate. The experiment was performed twice independently.
transcription profiling by array
Aiko Sato-Otsubo, Ayana Kon, Kenichi Yoshida, Masashi Sanada, Seishi Ogawa, Yasunobu Nagata, Yusuke Sato