E-GEOD-46920 - Transcripts induced by exposure to SLE serum in healthy blood monocytes

Status
Released on 3 June 2014, last updated on 9 June 2014
Organism
Homo sapiens
Samples (12)
Arrays (2)
Protocols (7)
Description
Monocytes from 3 healthy donors were cultured for 6 hours in the presence of 20% serum from three newly diagnosed, untreated SLE patients. Microarray analysis was then performed upon normalizing the gene expression levels of samples incubated with SLE sera to those incubated with autologous serum. Monocytes from 3 healthy donors were cultured for 6 hours in the presence of 20% serum from three newly diagnosed, untreated SLE patients. Microarray analysis was then performed upon normalizing the gene expression levels of samples incubated with SLE sera to those incubated with autologous serum.
Experiment type
transcription profiling by array 
Contacts
Alicia Rodriquez-Pla, Alisa Gotte, Holden Maecker, Jacques Banchereau, Jose Rossello-Urgell, Karolina A Palucka, Lorien Nassi, Lynda Bennett, Marilynn Punaro, Nicole Baldwin, Pinakeen Patel, Victoria Cantrell, Virginia Pascual
Citation
IFN Priming Is Necessary but Not Sufficient To Turn on a Migratory Dendritic Cell Program in Lupus Monocytes. Rodriguez-Pla A, Patel P, Maecker HT, Rossello-Urgell J, Baldwin N, Bennett L, Cantrell V, Baisch J, Punaro M, Gotte A, Nassi L, Wright T, Palucka AK, Banchereau J, Pascual V. , Europe PMC 24829414
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-46920.idf.txt
Sample and data relationshipE-GEOD-46920.sdrf.txt
Raw data (1)E-GEOD-46920.raw.1.zip
Processed data (1)E-GEOD-46920.processed.1.zip
Array designsA-AFFY-33.adf.txt, A-AFFY-34.adf.txt
Links