E-GEOD-46907 - Differentially expressed transcripts in SLE blood monocytes
Released on 3 June 2014, last updated on 7 June 2014
To better characterize the molecules that could potentially confer antigen presenting capacity to SLE monocytes, we assessed their gene expression profile. Blood monocytes from five healthy controls and five pediatric SLE patients were isolated using CD14+ selection. Because drugs used to treat SLE could induce considerable transcriptional changes, we selected active, newly diagnosed patients who had never received oral or intravenous (IV) medications.
transcription profiling by array
Alicia Rodriquez-Pla, Alisa Gotte, Holden Maecker, Jacques Banchereau, Jose Rossello-Urgell, Karolina A Palucka, Lorien Nassi, Lynda Bennett, Marilynn Punaro, Nicole Baldwin, Pinakeen Patel, Victoria Cantrell, Virginia Pascual
IFN Priming Is Necessary but Not Sufficient To Turn on a Migratory Dendritic Cell Program in Lupus Monocytes. Rodriguez-Pla A, Patel P, Maecker HT, Rossello-Urgell J, Baldwin N, Bennett L, Cantrell V, Baisch J, Punaro M, Gotte A, Nassi L, Wright T, Palucka AK, Banchereau J, Pascual V. , Europe PMC 24829414