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E-GEOD-46718 - WTAP is a novel oncogenic protein in Acute Myeloid Leukemia

Status
Released on 22 January 2014, last updated on 1 June 2014
Organism
Homo sapiens
Samples (4)
Protocols (4)
Description
Acute myeloid leukemia (AML) continues to have the lowest survival rates of all leukemias. Therefore, new therapeutic strategies are urgently needed to improve clinical outcomes for AML patients. Here, we report a novel role for Wilms’ tumor 1-associated protein (WTAP) in pathogenesis of AML. We have performed RNA-Seq in K562 cells with knockdown of WTAP to ascertain which genes it regulates. We have 2 replicates of total RNA for K562 cells and 2 replicates with WTAP knocked down
Experiment type
RNA-seq of coding RNA 
Contacts
Philip James Uren <uren@usc.edu>, Luiz O Penalva, Philip J Uren
Citation
WTAP is a novel oncogenic protein in acute myeloid leukemia. Bansal H, Yihua Q, Iyer SP, Ganapathy S, Proia D, Penalva LO, Uren PJ, Suresh U, Carew JS, Karnad AB, Weitman S, Tomlinson GE, Rao MK, Kornblau SM, Bansal S. , PMID:24413322
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-46718.idf.txt
Sample and data relationshipE-GEOD-46718.sdrf.txt
Processed data (1)E-GEOD-46718.processed.1.zip
Additional data (1)E-GEOD-46718.additional.1.zip
Links