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E-GEOD-46306 - Genome-wide DNA methylation in cervical tissue

Status
Released on 6 January 2014, last updated on 20 January 2014
Organism
Homo sapiens
Samples (44)
Array (1)
Protocols (5)
Description
The aim of this study was to identify new candidate genes that are differentially methylated in squamous cell carcinoma compared to the DNA samples from cervical intraepithelial neoplasia grade 3 (CIN3) and normal cervical scrapes. The Illumina Infinium Human Methylation 450 K BeadChip method identifies genome-wide DNA methylation changes in CpG islands, CpG shores and shelves. In this study 20 normal cervical samples (HPV negative), 18 samples with CIN3 lesions (HPV positive) and 6 cervical cancer tissues (HPV positive) were included.
Experiment type
methylation profiling by array 
Contacts
Magdalena Grce, Nina Milutin-Gašperov, Sanja A Farkas, Torbjörn K Nilsson
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-46306.idf.txt
Sample and data relationshipE-GEOD-46306.sdrf.txt
Processed data (1)E-GEOD-46306.processed.1.zip
Additional data (2)E-GEOD-46306.additional.1.zip, E-GEOD-46306.additional.2.zip
Array designA-GEOD-13534.adf.txt
Links