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E-GEOD-46262 - Studies on progenitor endothelial cells; exploring mechanisms for improvement of cardiovascular diseases

Status
Released on 24 February 2016, last updated on 27 February 2016
Organism
Homo sapiens
Samples (20)
Array (1)
Protocols (5)
Description
Transcriptomic analysis of primary CD34+ cells. CD34+ cell were induced in vitro with hypoxia (3 hours), high glucose and high glucose plus hypoxia. Subsequently, the effect of metformin (anti-diabetic drug) on all conditions was studied to take advantage of transcriptomics to prospectively explore the mechanism of this drug to reduce the risk of cardiovascular diseases in type II diabetic patients. Total RNA isolated from 20 samples; 10 different conditions each has 2 repeats; labeled, and hybridized to Affymetrix Human Gene 1.0 ST Array.
Experiment type
transcription profiling by array 
Contacts
Sherin Bakhashab <sbakhashab@kau.edu.sa>, Farid Ahmed, Hans-Juergen Schulten, Iokim Spyridopoulos, Jayapal Manikandan, Jolanta Weaver, Mohammed H Alqahtani, Sahira Lary
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-46262.idf.txt
Sample and data relationshipE-GEOD-46262.sdrf.txt
Raw data (1)E-GEOD-46262.raw.1.zip
Processed data (1)E-GEOD-46262.processed.1.zip
Array designA-AFFY-141.adf.txt
Links