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E-GEOD-46262 - Studies on progenitor endothelial cells; exploring mechanisms for improvement of cardiovascular diseases

Released on 24 February 2016, last updated on 27 February 2016
Homo sapiens
Samples (20)
Array (1)
Protocols (5)
Transcriptomic analysis of primary CD34+ cells. CD34+ cell were induced in vitro with hypoxia (3 hours), high glucose and high glucose plus hypoxia. Subsequently, the effect of metformin (anti-diabetic drug) on all conditions was studied to take advantage of transcriptomics to prospectively explore the mechanism of this drug to reduce the risk of cardiovascular diseases in type II diabetic patients. Total RNA isolated from 20 samples; 10 different conditions each has 2 repeats; labeled, and hybridized to Affymetrix Human Gene 1.0 ST Array.
Experiment type
transcription profiling by array 
Sherin Bakhashab <>, Farid Ahmed, Hans-Juergen Schulten, Iokim Spyridopoulos, Jayapal Manikandan, Jolanta Weaver, Mohammed H Alqahtani, Sahira Lary
Investigation descriptionE-GEOD-46262.idf.txt
Sample and data relationshipE-GEOD-46262.sdrf.txt
Raw data (1)
Processed data (1)
Array designA-AFFY-141.adf.txt