Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-45804 - Gene expression data from MCF-7 cells treated with Lacciac Acid A
Released on 3 September 2013, last updated on 16 June 2015
Lacciac Acid A was indentified as an inhibitor of DMNT1. MCF-7 cells were treated with Lacciac Acid A (200 uM) for 5 days. Changes in gene expression were identified by using Affymetrix Human gene ST1.0 arrays. We used microarrays to determine global changes in gene expression upon treatment with Lacciac Acid A an inhibitor of DMNT1. MCF-7 cells near mid passage were treated with Lacciac Acid A for 5 days. RNA was extracted and hybridized on Affymetrix microarrays. Treated and untreated cells were from the same cell passage. Two sample sets from the same passage and the third set from the previous passage were used.
transcription profiling by array
Thomas B Bair <firstname.lastname@example.org>, Bo-uan Wu, Charles Brenner, Diane E Cryderman, Lori L Wallrath, Rebecca Fagan
Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1. Fagan RL, Cryderman DE, Kopelovich L, Wallrath LL, Brenner C.