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E-GEOD-45804 - Gene expression data from MCF-7 cells treated with Lacciac Acid A

Status
Released on 3 September 2013, last updated on 16 June 2015
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (7)
Description
Lacciac Acid A was indentified as an inhibitor of DMNT1. MCF-7 cells were treated with Lacciac Acid A (200 uM) for 5 days. Changes in gene expression were identified by using Affymetrix Human gene ST1.0 arrays. We used microarrays to determine global changes in gene expression upon treatment with Lacciac Acid A an inhibitor of DMNT1. MCF-7 cells near mid passage were treated with Lacciac Acid A for 5 days. RNA was extracted and hybridized on Affymetrix microarrays. Treated and untreated cells were from the same cell passage. Two sample sets from the same passage and the third set from the previous passage were used.
Experiment type
transcription profiling by array 
Contacts
Thomas B Bair <thomas-bair@uiowa.edu>, Bo-uan Wu, Charles Brenner, Diane E Cryderman, Lori L Wallrath, Rebecca Fagan
Citation
Laccaic Acid A Is a Direct, DNA-competitive Inhibitor of DNA Methyltransferase 1. Fagan RL, Cryderman DE, Kopelovich L, Wallrath LL, Brenner C.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-45804.idf.txt
Sample and data relationshipE-GEOD-45804.sdrf.txt
Raw data (1)E-GEOD-45804.raw.1.zip
Processed data (1)E-GEOD-45804.processed.1.zip
Array designA-AFFY-141.adf.txt
Links