Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-45641 - Intestine-adapted bacterial symbiont response to polysaccharide rich and polysaccharide deficient diets in mice lacking fucosyltransferase-2

Status
Released on 21 April 2014, last updated on 28 April 2014
Organism
Bacteroides thetaiotaomicron
Samples (18)
Array (1)
Protocols (5)
Description
Analysis of Bacteroides thetaiotaomicron (BT) from the ceca of ex-germ free Fut2+ or Fut2- mice on polysaccharide rich or glucose rich polysaccharide deficient diet. BT is involved in the breakdown of plant polysaccharides and is also efficiently utilizes host glycans. BT-colonized mice represent a human gut ecosystem model. Results identify genes that may endow flexibility in adapting to dietary changes by mucosal foraging depending on host fucosylation status In vitro transcriptional profiles of Bacteroides thetaiotaomicron obtained from ceca of ex-germ free Fut2+ or Fut2- mice on polysaccharide rich or glucose rich polysaccharide deficient diet.
Experiment type
transcription profiling by array 
Contacts
Angela M Marcobal <marcobal@stanford.edu>, Justin L Sonnenburg, Purna Kashyap
Citation
Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota. Kashyap PC, Marcobal A, Ursell LK, Smits SA, Sonnenburg ED, Costello EK, Higginbottom SK, Domino SE, Holmes SP, Relman DA, Knight R, Gordon JI, Sonnenburg JL. , PMID:24062455
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-45641.idf.txt
Sample and data relationshipE-GEOD-45641.sdrf.txt
Raw data (1)E-GEOD-45641.raw.1.zip
Processed data (1)E-GEOD-45641.processed.1.zip
Array designA-GEOD-1821.adf.txt
Links