E-GEOD-45564 - Expression data in the presence of miR-29a inhibition in human dermal fibroblast cells
Released on 28 October 2013, last updated on 10 July 2015
miR-29 can target many gene transcripts encoding extracellular matrix proteins. To unravel novel targets, we used microarray analysis to detect global gene expression changes when inhibiting endogenous miR-29. Total RNA from human dermal fibroblast cells after 48 h treatment with miR-29a inhibitor or control inhibitor were isolated and subjected to whole gene expression microarray analysis.
transcription profiling by array
Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a. Zhang P, Huang B, Xu X, Sessa WC.