E-GEOD-45245 - Gene expression regulation by miR-145 in pancreatic cancer
Released on 19 March 2013, last updated on 2 June 2014
miR-145 is a tumor suppressor miRNA in various malignancies including pancreatic cancer. Identification of miR-145 targets can lead to more understanding of the development of pancreatic cancer. Therefore, in this project, we aimed to characterize the changes of transcriptomes caused by miR-145 to identify more miR-145 target transcripts. cDNA microarray was used to compare transcriptomes 48 hr after transfection of miR-145 mimics or control scramble RNA in a pancreatic cancer cell line, Mia-PaCa2.
transcription profiling by array
Tai-Chung Huang <firstname.lastname@example.org>, Akhilesh Pandey, Tai C Huang, Yi Yang