E-GEOD-4512 - Transcription profiling by array of heterozygous/homozygous mice for human CFTR vs wild type to identify genes responsive to normal hCFTR
Released on 23 November 2007, last updated on 1 October 2015
Identification of Genes Responsive to the Expression of Normal Human CFTR Experiment Overall Design: To discern the effects of increased expression of normal human CFTR, lung mRNA levels were assessed in mice expressing the normal human CFTR cDNA under control of the Sftpc gene promoter in respiratory epithelial cells of adult mice. Triplicate samples from SP-C-hCFTRtg/tg, SP-C-hCFTRtg/-, and wild type mice were compared.
transcription profiling by array, co-expression, individual genetic characteristics