E-GEOD-44837 - Gene methylation profile of breast cancer cells
Released on 12 July 2013, last updated on 24 July 2013
We compared the gene methylation profile of 26 breast cancer cell lines to identify variations associated with different phenotypes and molecular subtype. The panel includes 13 estrogen receptor negative (ER-) and 13 ER+ cell lines. Four of the ER- cell lines and 5 of the ER+ cell lines are HER2 positive. Bisulphite converted DNA from the 26 samples was hybridised to the Illumina Infinium Human Methylation450 Beadchip.
methylation profiling by array
Francescopaolo Di Cello <email@example.com>, Cynthia A Zahnow, Huili Li
Methylation of the claudin 1 promoter is associated with loss of expression in estrogen receptor positive breast cancer. Di Cello F, Cope L, Li H, Jeschke J, Wang W, Baylin SB, Zahnow CA. , Europe PMC 23844228