Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-44356 - Expression data from wild-type and HMGN1 knockout mice injected with N-nitrosodiethylamine
Released on 24 August 2013, last updated on 8 July 2015
HMGN1 contributes to the shortened latency of liver tumorigenesis by changing a chromatin structure and expression of relevant genes To assess the molecular mechanisms underlying accelerated tumor development in Hmgn1-/- mice, we performed the gene expression profiling of liver cells at early stages Expression profiles has been compared between Hmgn1+/+ and Hmgn1-/- mice livers at 4 weeks after birth and at 12 weeks after DEN or saline (control) injection at 4 weeks
transcription profiling by array
Yuri Postnikov <email@example.com>, Nina Bubunenko, Yuri V Postnikov
Loss of the nucleosome-binding protein HMGN1 affects the rate of N-nitrosodiethylamine-induced hepatocarcinogenesis in mice. Postnikov YV1, Furusawa T, Haines DC, Factor VM, Bustin M.