E-GEOD-44056 - Gene expression data from lateral ventricle choroid plexuses of developing and adult rats
Released on 17 September 2013, last updated on 2 June 2014
Choroid plexuses (CP) develop early during development. They form a barrier between the blood and the cerebrospinal fluid, and fulfill important protective and nutritive functions. We used Affymetrix microarrays to assess whether CP of the lateral ventricles (LVCP) have similar functions in developing and adult brain. We identified distinct families of protective and transport genes and found that most of these genes were already well expressed during development. 2 batches of CP from embryonic day E19, postnatal day 2 and adult rats were processed for RNA extraction and hybridization on Affymetrix microarrays.
transcription profiling by array
Ingrid Kratzer <email@example.com>, Jean F Ghersi-Egea, Nathalie Strazielle
Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection. Kratzer I, Liddelow SA, Saunders NR, Dziegielewska KM, Strazielle N, Ghersi-Egea JF. , Europe PMC 23915922
Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach. Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, Lindsay H, Wakefield MJ, Strazielle N, Kratzer I, Mï¿½llgï¿½rd K, Ghersi-Egea JF, Saunders NR. , Europe PMC 23843944