Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-42208 - Hdac6 is a stem-cell specific modulator of Tip60-p400 function (gene expression)
Released on 20 November 2013, last updated on 2 December 2013
To identify the functional role of Hdac6 in embryonic stem cells, we examined gene expression changes in mouse ES cells upon Tip60, Hdac6 and double knockdown. Two biological replicates each for control (GFP), Tip60, Hdac6 and double KD in E14 mouse ESCs. Lentiviral-based shRNA was used and gene expression changes were determined 3 days after KD. The global gene expression profiles of Tip60, Hdac6 and double KD were compared to control KD cells.
transcription profiling by array
Andrew H Coles, Feixia Chu, James F Carey, Jui-Hung Hung, Poshen B Chen, Taylor L Hickman, Thomas G Fazzio, Zhiping Weng