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E-GEOD-42208 - Hdac6 is a stem-cell specific modulator of Tip60-p400 function (gene expression)

Status
Released on 20 November 2013, last updated on 2 December 2013
Organism
Mus musculus
Samples (8)
Array (1)
Protocols (7)
Description
To identify the functional role of Hdac6 in embryonic stem cells, we examined gene expression changes in mouse ES cells upon Tip60, Hdac6 and double knockdown. Two biological replicates each for control (GFP), Tip60, Hdac6 and double KD in E14 mouse ESCs. Lentiviral-based shRNA was used and gene expression changes were determined 3 days after KD. The global gene expression profiles of Tip60, Hdac6 and double KD were compared to control KD cells.
Experiment type
transcription profiling by array 
Contacts
Andrew H Coles, Feixia Chu, James F Carey, Jui-Hung Hung, Poshen B Chen, Taylor L Hickman, Thomas G Fazzio, Zhiping Weng
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-42208.idf.txt
Sample and data relationshipE-GEOD-42208.sdrf.txt
Raw data (1)E-GEOD-42208.raw.1.zip
Processed data (1)E-GEOD-42208.processed.1.zip
Array designA-GEOD-10333.adf.txt
Links