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E-GEOD-42025 - Chromatin proteins linked to dosage compensation in Drosophila captured by ChIP-mass spectrometry
Released on 6 November 2012, last updated on 11 March 2013
We report the usage of ChIP-mass spectrometry in identifying proteins and histone modifications involved in Drosophila dosage compensation. We identified a chromatin targeting factor, CG4747, that is involved in recognition of H3K36me3 and robust recruitment of the Drosophila MSL complex to its correct targets on the male X chromosome. ChIP-seq with PAP antibody of Drosophila larvae expressing C-terminally TAP-tagged CG4747.
Peter Kharchenko <email@example.com>, Charlotte Wang, Mitzi Kuroda