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E-GEOD-41453 - Gene expression in the kidneys of two spontaneously hypertensive rat strains at 3 and 6 weeks of age

Released on 3 July 2015, last updated on 19 August 2015
Rattus norvegicus
Samples (18)
Array (1)
Protocols (6)
We examined gene expression profiles in the rat kidneys using genome-wide microarray technology, and determined gene expression profiles in 3 rat strains: normotensive WKY, spontaneously hypertensive rats (SHR), and stroke-prone SHR (SHRSP). To identify candidate genes involved in the genesis of hypertension in the SHR strains, we compared the gene expression levels at 3 and 6 weeks of age, isolated 407 genes showing a more than 4-fold increase or a less than 1/4-fold decrease. The rat kidneys derived from normotensive WKY, spontaneously hypertensive rats (SHR), and stroke-prone SHR (SHRSP) were examined. Each strain was run in triplicate.
Experiment type
transcription profiling by array 
Daisuke Okuzaki, Hiromichi Yamanishi, Hiroshi Nojima, Kazunori Shimada, Momoko Yoshida, Yuko Watanabe
Investigation descriptionE-GEOD-41453.idf.txt
Sample and data relationshipE-GEOD-41453.sdrf.txt
Raw data (1)
Processed data (1)
Array designA-GEOD-14745.adf.txt