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E-GEOD-3846 - Transcription profiling of healthy human volunteers after consumin red wine vs. controls to investigate the cardioprotective effect of red wine

Status
Released on 1 November 2007, last updated on 28 September 2015
Organism
Homo sapiens
Samples (108)
Array (1)
Protocols (2)
Description
The aim of this study was to measure the influence of beverages on blood gene expression. We wanted to explore the underlying mechanisms of the cardioprotective effects of red wine. Experiment Overall Design: Six healthy volunteers participated in this randomized controlled cross-over experiment. On 4 independent days they had 4 different beverages (500mL each: grape juice, red wine, 40g diluted ethanol, water). Blood samples were taken at baseline, 1, 2, 4, 12 hours after the drink together with standardized nutrition. RNA of 120 PBL samples was hybridized on Affymetrix microarrays. Three sources of variations were examined: individual, time and beverage.
Experiment types
transcription profiling by array, compound treatment, individual comparison, time series
Contact
Citation
Analysis with respect to instrumental variables for the exploration of microarray data structures. Florent Baty, Michaël Facompré, Jan Wiegand, Joseph Schwager, Martin H Brutsche.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-3846.idf.txt
Sample and data relationshipE-GEOD-3846.sdrf.txt
Raw data (3)E-GEOD-3846.raw.1.zip, E-GEOD-3846.raw.2.zip, E-GEOD-3846.raw.3.zip
Processed data (1)E-GEOD-3846.processed.1.zip
Array designA-AFFY-33.adf.txt
Links