E-GEOD-37363 - Transcription profiling by array of TET2 wild type and TET2 mutant patients with diffuse large B-cell derived lymphoma

Status
Released on 10 October 2013, last updated on 1 May 2015
Organism
Homo sapiens
Samples (9)
Array (1)
Protocols (6)
Description
Global gene expression in TET2 mutant and Wild type patients. We performed an integrated analysis of global DNA methylation and gene expression data to investigate the effects of DNA hypermethylation on gene expression. Total RNA was isolated from 4 TET2mut and 5 TET2wt were isolated using standard RNAeasy kit protocol (Qiagen). Their gene expression profiles were obtained using the[HuGene-1_0-st] Affymetrix.
Experiment type
transcription profiling by array 
Contacts
Anders B Nielsen, Anja Pedersen, Christoffer Hother, Elisabeth Ralfkiaer, Fazila Asmar, Jesper Christensen, Kirsten Gronbaek, Kristian Helin, Marianne T Pedersen, Peter D Brown, Ulrik Ralfkiaer, Vasu Punj
Citation
Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma. Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A, Nielsen AB, Hother C, Ralfkiaer U, Brown P, Ralfkiaer E, Helin K, Gr�nb�k K. , Europe PMC 23831920
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-37363.idf.txt
Sample and data relationshipE-GEOD-37363.sdrf.txt
Raw data (1)E-GEOD-37363.raw.1.zip
Processed data (1)E-GEOD-37363.processed.1.zip
Array designA-AFFY-141.adf.txt
Links