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E-GEOD-35976 - Genome wide array analysis of endosseous implant adherent cellular phenotypes

Status
Released on 27 September 2012, last updated on 18 October 2012
Organism
Rattus norvegicus
Samples (16)
Array (1)
Protocols (8)
Description
Objective: to identify the early molecular processes involved in osseointegration associated with a micro roughened and nanosurface featured implants. Thirty-two titanium implants with surface topographies exhibiting nanoscale features (AT-I) and microrough surface without nanoscale features (AT-II) were placed in the tibiae of 8 rats and subsequently harvested at 2 and 4 days after placement. Total RNA was isolated from cells adherent to retrieved implants. A whole genome microarray using the Affymetrix Rat gene 1.1 ST Array was used to describe the gene expression profiles that were differentially regulated by the implant surfaces.
Experiment type
transcription profiling by array 
Contacts
Lyndon Cooper <geo@ncbi.nlm.nih.gov>, Ghadeer N Thalji, Lyndon F Cooper
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-35976.idf.txt
Sample and data relationshipE-GEOD-35976.sdrf.txt
Raw data (1)E-GEOD-35976.raw.1.zip
Processed data (1)E-GEOD-35976.processed.1.zip
Array designA-GEOD-11534.adf.txt
Links