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E-GEOD-35578 - Correlation between gene expression responses to FUS, EWS, and TAF15 reduction and the stress granule sequestering capacity

Status
Released on 7 February 2012, last updated on 15 February 2012
Organism
Homo sapiens
Samples (6)
Array (1)
Protocols (8)
Description
Analysis of differentially expressed genes after siRNA mediated knock-down of the FET-family of proteins; the FUS, EWS, and TAF15 proteins. The FET-proteins are thought to function as transcription factors, and this hypothesis is tested in the present study. Results provide important information of the genes which expression are controlled by the FET-family of proteins. Total RNA obtained HEK293-cells transfected with siRNA targeted against the FUS, EWS, or TAF15 mRNA, or a combination of all three of them. Control cells are transfected with an equal amount of unspecific siRNA without known targets.
Experiment type
transcription profiling by array 
Contacts
Yonglun Luo <yonglun.luo@hum-gen.au.dk>, Anders L Nielsen, Jenny Blechingberg
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-35578.idf.txt
Sample and data relationshipE-GEOD-35578.sdrf.txt
Processed data (1)E-GEOD-35578.processed.1.zip
Additional data (1)E-GEOD-35578.additional.1.zip
Array designA-MEXP-1173.adf.txt
Links