Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-35362 - Infection of bone marrow derived macrophages with M. tuberculosis CDC1551
Released on 11 July 2012, last updated on 4 May 2014
Mycobacterium tuberculosis H37Rv
I infected 8 flasks of resting murine bone marrow derived macrophages with M. tuberculosis CDC1551. Individual samples of intracellular Mtb were collected at 2hr, and days 2,4,6,8,10,12, and 14 post-infection using the GTC (guanidine thiocyanate) method as previously published. A 2hr "no macrophage" control was used as a common denominator in the two-color hybridizations. I have two independent biological replicates of this experiment. Groups of assays that are related as part of a time series. Time: culture time post-infection time_series_design
transcription profiling by array
Kyle Herman Rohde <email@example.com>, David Russell
Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection. Rohde KH, Veiga DF, Caldwell S, Balázsi G, Russell DG. , PMID:22737072