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E-GEOD-35129 - Expression data from Integrin-linked kinase (ILK)-deficient epidermis

Status
Released on 18 January 2012, last updated on 23 January 2012
Organism
Mus musculus
Samples (10)
Array (1)
Protocols (8)
Description
ILK is essential for proper development of hair follicles, and for epidermal integrity and repair after injury. To better understand the pathways modulated by ILK in the epidermis, we compared the transcriptomes of ILK-deficient and -expressing epidermis using microarray analyses. Ilktm1Star (with floxed Ilk alleles) and Tg(KRT14-cre)1Amc/J mice were bred, and the resulting mice were bred again with Ilktm1Star mice, to generate animals heterozygos for the KRT14-cre transgene and either heterozygous (ILK-expressing) or homozygous (ILK-deficient) for the floxed Ilk alleles. The epidermis of 3 day-old animals was harvested and used to prepare RNA for the microarrays. The animals used were littermates. RNA from the epidermis of five ILK-deficient and five ILK-expressing mice were used.
Experiment type
transcription profiling by array 
Contacts
David E Carter <dcarter@robarts.ca>, Alena Rudkouskaya, David Judah, Lina Dagnino
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-35129.idf.txt
Sample and data relationshipE-GEOD-35129.sdrf.txt
Raw data (1)E-GEOD-35129.raw.1.zip
Processed data (1)E-GEOD-35129.processed.1.zip
Array designA-AFFY-130.adf.txt
R ExpressionSetE-GEOD-35129.eSet.r
Links