Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-34925 - Expression data from knockdown of G9a in MDA-MB231 cells
Released on 7 January 2012, last updated on 17 August 2015
G9a is an H3K9m2 methyltransferase, which is critical in controlling gene suppression and DNA methylation. We used microarray analysis to identify the target genes that are regulated by G9a in MDA-MB231 cells, in which E-cadherin is silenced. G9a expression was stably knocked-down in MDA-MB231 cells. RNA from this clone and parental (control) cells were purified for microarray analysis.
transcription profiling by array
Binhua P Zhou, Dong Chenfang
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Dong C, Yuan T, Wu Y, Wang Y, Fan TW, Miriyala S, Lin Y, Yao J, Shi J, Kang T, Lorkiewicz P, St Clair D, Hung MC, Evers BM, Zhou BP.
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer. Dong C, Wu Y, Yao J, Wang Y, Yu Y, Rychahou PG, Evers BM, Zhou BP.