E-GEOD-3431 - Transcription profiling of yeast S. cerevisiae over three successive metabolic cycles
Submitted on 10 October 2005, released on 24 June 2007, last updated on 27 March 2012
Budding yeast grown under continuous, nutrient-limited conditions exhibit robust, highly periodic cycles in the form of respiratory bursts. Microarray studies reveal that over half of the yeast genome is expressed periodically during these metabolic cycles. Genes encoding proteins having a common function exhibit similar temporal expression patterns, and genes specifying functions associated with energy and metabolism tend to be expressed with exceptionally robust periodicity. Essential cellular and metabolic events occur in synchrony with the metabolic cycle, demonstrating that key processes in a simple eukaryotic cell are compartmentalized in time. This data set contains the raw affymetrix gene expression data over three successive metabolic cycles. 12 time intervals per cycle, ~25 min per time interval.
transcription profiling by array, co-expression, time series
Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Benjamin P Tu,Andrzej Kudlicki,Maga Rowicka,Steven L McKnight. Science :1152-8 (2005)