E-GEOD-34011 - Expression data from mouse intestine: BALB/c MTHFR+/+ on control diet vs BALB/c MTHFR+/- on folate deficient diet

Status
Released on 3 December 2013, last updated on 1 May 2015
Organism
Mus musculus
Samples (8)
Array (1)
Protocols (7)
Description
Previous studies in our laboratory have shown that low folate diet (control diet with 2mg folate/kg, low folate diet with 0.3mg folate/kg) can induce intestinal tumors in BALB/c mice. We used microarrays to compare MTHFR+/+ BALB/c mice fed control diet and MTHFR+/- BALB/c mice fed low folate diet. After weaning, 4 BALB/c Mthfr +/+ mice were fed with a control diet (CD, 2mg folate/kg) and 4 BALB/c Mthfr +/- mice were fed a low folate diet (FD, 0.3mg folate/kg) for 1 year. Both diets contain succinylsulfanthiozole (1%) to prevent folate synthesis by intestine microbial biota.
Experiment type
transcription profiling by array 
Contacts
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-34011.idf.txt
Sample and data relationshipE-GEOD-34011.sdrf.txt
Raw data (1)E-GEOD-34011.raw.1.zip
Processed data (1)E-GEOD-34011.processed.1.zip
Array designA-AFFY-130.adf.txt
Links