E-GEOD-33627 - Expression data of IL-18 generated murine NK cells

Released on 10 July 2012, last updated on 22 September 2015
Mus musculus
Samples (6)
Array (1)
Protocols (8)
We analyzed gene expression profiles of IL-18 generated murine NK cells in comparison to unstimulated, freshly isolated splenic NK cells. We identified a set of 1414 Affymetrix probe sets showing significant misregulation (Welch's T-test, p<0.05; Benjamini-Hochberg FDR corrected). IL-18 generated as well as unstimulated NK cells were isolated in three independent preparations and used for RNA extraction and hybridization on Affymetrix microarrays.
Experiment type
transcription profiling by array 
Rene Deenen <rene.deenen@uni-duesseldorf.de>, Annette Thiel, Benedikt Jacobs, Claudia Papewalis, Evelyn Ullrich, Holger S Willenberg, Klaus L Meyer, Laurence Zitvogel, Margret Ehlers, Matthias Schott, René Deenen, Sven Schinner, Werner A Scherbaum
Immunoregulatory natural killer cells suppress autoimmunity by down-regulating antigen-specific CD8+ T cells in mice. Ehlers M, Papewalis C, Stenzel W, Jacobs B, Meyer KL, Deenen R, Willenberg HS, Schinner S, Thiel A, Scherbaum WA, Ullrich E, Zitvogel L, Schott M.
Investigation descriptionE-GEOD-33627.idf.txt
Sample and data relationshipE-GEOD-33627.sdrf.txt
Raw data (1)E-GEOD-33627.raw.1.zip
Processed data (1)E-GEOD-33627.processed.1.zip
Array designA-AFFY-130.adf.txt