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E-GEOD-33451 - Genome-wide analysis of gene transcription in myocardium of mice transgenically expressing human cardiolipin synthase 1 (hCLS1) in cardiac tissue

Status
Released on 5 November 2011, last updated on 17 November 2011
Organism
Mus musculus
Samples (8)
Array (1)
Protocols (6)
Description
Analysis of the transcriptome of cardiac tissue from mice transgenically expressing human cardiolipin synthesis. The hypothesis tested was that cardiac specific transgenic expression of cardiolipin synthase alters myocardial lipidomic flux resulting in compensatory metabolic gene transcriptional changes that will attenuate pathological environmental and dietary insults on bioenergetics. Total RNA obtained from cardiac tissue from transgenic cardiac specific expressing human cardiolipin synthase 1 (hCLS1) mouse model at 4 months of age compared to wildtype littermates
Experiment type
transcription profiling by array 
Contacts
Michael Andrew Kiebish <kiebish@wustl.edu>, Michael A Kiebish, Richard W Gross, Xianlin Han
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-33451.idf.txt
Sample and data relationshipE-GEOD-33451.sdrf.txt
Processed data (1)E-GEOD-33451.processed.1.zip
Array designA-MEXP-1174.adf.txt
Links