E-GEOD-33226 - Genome wide DNA methylation analysis of leukemia and reprogrammed leukemia cells (gene expression)

Status
Released on 1 October 2012, last updated on 18 October 2012
Organism
Homo sapiens
Samples (8)
Array (1)
Protocols (7)
Description
We analyzed the methylation pattern of a well characterized leukemia cell line, named K562. Furthermore, we decided to investigate how the malignant epiegenome change during the reprogramming process We used Affymatrix expression microarrays analysis to investigate the relation between expression and methylation in leukemia and reprogrammed leukemia (LiPS). We show that the erasure of the epigenetic aberrancies have functional consequences on leukemia phenotype
Experiment type
transcription profiling by array 
Contacts
Alexander Ebralidze, Annalisa Di Ruscio, Giovanni Amabile, Sarawut Wongphayak, Touati Benoukraf
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-33226.idf.txt
Sample and data relationshipE-GEOD-33226.sdrf.txt
Raw data (1)E-GEOD-33226.raw.1.zip
Processed data (1)E-GEOD-33226.processed.1.zip
Array designA-AFFY-141.adf.txt
Links