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E-GEOD-33078 - Comparison of intestinal surface CD3- refractory celiac disease type II (RCDII) cell lines with intestinal surface CD3+ cell lines of non-RCDII patients

Status
Released on 11 June 2012, last updated on 21 June 2012
Organism
Homo sapiens
Samples (22)
Array (1)
Protocols (8)
Description
Analysis of transcriptional differences between aberrant (surface CD3-) RCDII cell lines and regular (surface CD3+) intraepithelial cell lines in order to characterize aberrant RCDII cells. All cell lines were cultured from duodenal biopsies of RCDII or non-RCDII (either celiac or non-celiac) patients. We compared 3 RCDII cell lines from RCDII patients P1-P3 with the following control cell lines: CD3+CD4+ T cell line from P1 and P3, CD3+CD8+ T cell line from P3 and mixed CD4/CD8+ T cell lines from non-RCDII patients. All control cells matched the phenotype of mature T cells (CD3+CD4+ and/or CD3+CD8+). Samples were randomly distributed among two BeadChips and measured in duplicates.
Experiment type
transcription profiling by array 
Contacts
Frederike Schmitz <f.schmitz@lumc.nl>, Allan Thompson, Frits Koning, Jennifer Tjon, Jeroen Bergen, Yuching Lai, Yvonne Kooy-Winkelaar
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-33078.idf.txt
Sample and data relationshipE-GEOD-33078.sdrf.txt
Processed data (1)E-GEOD-33078.processed.1.zip
Additional data (1)E-GEOD-33078.additional.1.zip
Array designA-MEXP-1171.adf.txt
Links